Unraveiling the Mystery: Jejunal Stenosis Post-Stroke: A Case Report

Authors

  • Priyaben Bhakta St. George’s University, School of Medicine, St. George’s, Grenada, West Indies
  • Diego Hanssen, MD Department of Surgery, Bronxcare Health System, New York City, NY, USA
  • David Fan, MD Department of Surgery, Bronxcare Health System, New York City, NY, USA

DOI:

https://doi.org/10.38179/ijcr.v4i1.296

Keywords:

jejunal stricture, ischemic enteritis, posterior cerebral artery stroke

Abstract

Background: Jejunal stenotic strictures are relatively rare but have significant clinical entities and various complex etiologies characterized by the narrowing or obstruction of the jejunum.

Case Report: The patient presented with a two-month history of abdominal pain, persistent nausea, bilious vomiting, and dizziness, following a left posterior cerebral artery (PCA) stroke. Workup and various imaging studies revealed stenosis of the 3rd and 4th portion of the proximal jejunum, leading to the decision to proceed with exploratory laparotomy with bowel resection and anastomosis. The histological examination of the 15cm jejunum resection revealed significant transmural inflammation, encompassing both acute and chronic components. The presence of ulcers and prominent lymphocyte infiltration was noted, along with granulation tissue and hypertrophic muscularis propria.

Conclusion: The absence of focal deficits and subsequent ischemic events, accompanied by a history of inflammatory bowel disease, suggested ischemic enteritis (IE) as the primary etiology. The patient exhibited a full recovery following the surgical intervention and reported normal gastrointestinal (GI) function. This case emphasizes the necessity for further research to gain a comprehensive understanding of the pathophysiology and optimal management approaches for jejunal stenosis. It further highlights the significance of considering IE in patients with persistent GI symptoms post-stroke.

References

Van Buren G 2nd, Teichgraeber DC, Ghorbani RP, Souchon EA. Sequential stenotic strictures of the small bowel leading to obstruction. World J Gastroenterol. 2007;13(40):5391-5393. PMID: 17879413. https://doi.org/10.3748/wjg.v13.i40.5391

Guglielmo FF, Anupindi SA, Fletcher JG, et al. Small Bowel Crohn Disease at CT and MR Enterography: Imaging Atlas and Glossary of Terms. Radiographics. 2020;40(2):354-375. PMID: 31951512.

https://doi.org/10.1148/rg.2020190091

Koshikawa Y, Nakase H, Matsuura M, et al. Ischemic enteritis with intestinal stenosis. Intest Res. 2016;14(1):89-95. PMID: 26884740. https://doi.org/10.5217/ir.2016.14.1.89

1. Tuz AA, Hasenberg A, Hermann DM, Gunzer M, Singh V. Ischemic stroke and concomitant gastrointestinal complications- a fatal combination for patient recovery. Frontiers. October 24, 2022. Accessed May 15, 2024. PMID: 36439129.

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1037330/full.

Ye D, Hu Y, Zhu N, et al. Exploratory Investigation of Intestinal Structure and Function after Stroke in Mice. Mediators Inflamm. 2021;2021:1315797. Published 2021 Feb 15. PMID: 33642941. https://doi.org/10.1155/2021/1315797

Schaller BJ, Graf R, Jacobs AH. Pathophysiological changes of the gastrointestinal tract in ischemic stroke. Am J Gastroenterol. 2006;101(7):1655-1665. PMID: 16863574. https://doi.org/10.1111/j.1572-0241.2006.00540.x

Huda T, Pandya B. Jejunal obstruction due to ischemic stricture: An unusual presentation. International Surgery Journal.

http://dx.doi.org/10.18203/2349-2902.isj20190378.

Koshikawa Y, Nakase H, Matsuura M, et al. Ischemic enteritis with intestinal stenosis. Intest Res. 2016;14(1):89-95. PMID: 26884740. https://doi.org/10.5217%2Fir.2016.14.1.89

Takeuchi N, Naba K. Small intestinal obstruction resulting from ischemic enteritis: a case report. Clin J Gastroenterol. 2013;6(4):281-286. PMID: 23990850. https://doi.org/10.1007/s12328-013-0393-y

Gonzalez AJ, Afraz S, Melendez-Rosado J, Schneider A. Isolated Jejunal Crohn's Disease Masquerading as Gastroparesis. Cureus. 2022;14(6):e26333. Published 2022 Jun 25. PMID: 35775060. https://doi.org/10.7759/cureus.26333

Exploratory Laparotomy showing dense adhesions involving stenotic jejunum.

Published

2024-05-28

How to Cite

Bhakta, P., Hanssen, D., & Fan, D. (2024). Unraveiling the Mystery: Jejunal Stenosis Post-Stroke: A Case Report . International Journal of Clinical Research, 4(1), 6-11. https://doi.org/10.38179/ijcr.v4i1.296